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|Title: ||The antiinflammatory activity of extracts from the root of Combretum dolichopetalum|
|Authors: ||Asuzu, I. U|
Adimorah, R. I.
|Keywords: ||Combretum dolichopetalum, root extract, carrageenin edema, .|
Croton oil edema, antiinflam mation
|Issue Date: ||5-Apr-1998|
|Publisher: ||Elsevier Science|
|Abstract: ||The methanol and chloroform extracts of the root of Combretum dolichopetalum were obtained and
gave yields of 6.48%
w/w and 0.38% w/w respectively. The methanol extract significantly inhibited car
ageenin-induced mouse paw edema in a dose-dependent manner after an oral treatment.
effect was achieved at a dose of 600 mg/kg and the result was comparable to that of indomethacin (10
mg/kg). The antiinflammatory activity of the chloroform extract against croton-oil induced mouse ear
edema was significant (p
< 0.001) and increased with the dose. The maximum effect (93%) was
achieved with 1.0 mg of the extract per ear. firstname.lastname@example.org|
|Appears in Collections:||Others|
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