http://repository.fuoye.edu.ng:80/handle/123456789/86 2026-04-16T23:21:53Z 2026-04-16T23:21:53Z ORIRE, OMOLOLA VICTORIA http://repository.fuoye.edu.ng:80/handle/123456789/1365 2016-07-08T09:57:03Z 2015-10-01T00:00:00Z

Title: DETECTION OF BIOACTIVE CONSTITUENTS IN Phyllanthus amarus USING THIN LAYER CHROMATOGRAPHY-BIOAUTOGRAPHIC METHOD AGAINST Staphylococcus aureus AND Coagulase negative staphylococcus aureus Authors: ORIRE, OMOLOLA VICTORIA Abstract: Throughout the history of drug development, natural products have provided a fundamental source of drugs for fighting infections. Like in many developing countries, new drugs are often not affordable in Nigeria. Approximately 60– 80% of the world's population still relies on traditional medicines as remedies for the treatment of common illnesses (Owolabi et al., 2007). Nascimento et al., (2000) stated that the World Health Organization (W.H.O) has ascribed medicinal plants as the best source of variety of drugs in combating serious diseases and it advocates that countries should venture into other aspects of traditional medicine. This should be with a view of identifying safe and effective remedies for ailments of both microbial and non-microbial organisms. Medicinal plants have been used for centuries as remedies for human diseases because they contain components of therapeutic value (Tanaka et al., 2002). In recent years, secondary plant metabolites (phytochemicals) have been extensively investigated as a source of medicinal agents. It is anticipated that phytochemicals with good antimicrobial activity will be used for the treatment of bacterial infections, fungi, and viruses.

2015-10-01T00:00:00Z OLOWOKERE, VICTORIA BUKOLA OJO, S.K.S http://repository.fuoye.edu.ng:80/handle/123456789/1357 2016-06-03T10:07:10Z 2015-10-01T00:00:00Z

Title: PROPHYLACTIC ACTIVITY OF Diodia scandens CRUDE EXTRACTS ON SWISS ALBINO RATS Authors: OLOWOKERE, VICTORIA BUKOLA; OJO, S.K.S Abstract: The aim of this study was to evaluate the prophylactic activity of Diodia scandens on Swiss albino rats challenged with Staphylococcus epidermidis. Twenty (20) Swiss albino rats of both sexes weighing (120-200) were housed in polycarbonated cages at ambient environmental condition of 23±2oC, 30-60% relative humidity. They were defasted for 4hour prior to treatment. Different concentrations of different extracts (50mg/kg and 100mg/kg) of Diodia scandens were given according to the weight of rats and were challenged with 0.5ml of 1×108 cfu/ml of Staphylococcus epidermidis in Mueller Hinton broth using 0.5 Mcfarland standards at the 4th day of the pre-treatment. The result showed aggressiveness, no fever or inflammation during the pre-treatment. After the organism challenge test it was observed that with some level of protection were offered by extract of Diodia scandens on the rats. Description: The protection offered by Diodia scandens after organism challenged test has shown that the plant is potent, effective and had boosted the immunity of the rats against Staphylococcus epidermidis. It was concluded that 50mg/kg and 100mg/kg of Diodia scandens was effective during pre-treatment and was not toxic on the rats.

2015-10-01T00:00:00Z BOSEDE BOLAJI, OGUNLEYE DR. L.E, OKORO http://repository.fuoye.edu.ng:80/handle/123456789/1342 2016-05-25T09:26:58Z 2015-09-01T00:00:00Z

Title: PREVALENCE OF DENGUE VIRUS IgM IN BLOOD SAMPLES OF PATIENTS FROM DIFFERENT STATES IN SOUTHWESTERN NIGERIA USING ELISA Authors: BOSEDE BOLAJI, OGUNLEYE; DR. L.E, OKORO Abstract: Dengue virus has been classified in the past years as family of flaviridae, genus flavivirus with specie name of Dengue virus. The study was conducted with the aim of detecting prevalence of dengue virus IgM among patient attending clinic for typhoid and malaria in different southwestern states in Nigeria. Objective is to improve dengue surveillance and diagnostic so that the quality of care for patient can be improve and the cost of and rate associated with malaria and typhoid and dengue can be reduce .the study was carried out on 26 fresh blood samples which was collected from children and adult reporting for typhoid and malaria in different states in southwestern Nigeria .Elisa kits was use for the experiment and microliter plate reader was used to read the result under the absorbance of 450nm,the result of study shows 13 samples as positive and 14 samples of blood negative .the percentage of result shows 53.1 positive and 48.1 negative .in conclusion the percentage of negatives result obtain in this study shows that dengue virus is not prevalent in southwestern part of Nigeria

2015-09-01T00:00:00Z SALIYUK, REBECCA NVAN http://repository.fuoye.edu.ng:80/handle/123456789/1307 2016-05-10T10:24:02Z 2015-10-01T00:00:00Z

Title: PREVALENCE OF ANTIBIOTIC RESISTANT ENTEROCOCCI ISOLATED FROM FOOD Authors: SALIYUK, REBECCA NVAN Abstract: Enterococci have continued to attract attention as emerging pathogen both in Hospital and the environment. Interest on their prevalence has therefore become of interest. Their resistance to multiple antibiotics was investigated from foods in Oye-Ekiti, Nigeria. From the 20 samples collected from food vendors which include: rice, beans, fufu and pounded yam were investigated for the presence of Enterococci. 3 (15%) were positive for enterococci. This study has revealed the prevalence of Enterococci strain in ready-to-eat-food in Oye-Ekiti, Nigeria. The enterococci showed resistant trait to a number of antibiotics. They do not show resistance to Gentamycin. The mere presence of Enterococci in food is indicative of poor sanitary quality of food, which may be from contaminated water. The result of this research reveals the need for proper hygiene and inspection of food outlets.

2015-10-01T00:00:00Z FATOYE, OLUWAFUNLOLA FUNTO http://repository.fuoye.edu.ng:80/handle/123456789/1302 2016-05-05T11:01:01Z 2015-10-01T00:00:00Z

Title: ASSAY OF ANTIBIOTIC PRODUCING MICROORGANISMS ISOLATED FROM DIFFERENT SOILS IN THE PREMISES OF FEDERAL UNIVERSITY OYE-EKITI Authors: FATOYE, OLUWAFUNLOLA FUNTO Abstract: A total of eight soil samples were collected from different sites within FUOYE environment and were analysed to determine the presence of antibiotic producing bacteria, fungi and actinomycete using Nutrient agar, Sabauraud dextrose agar and Glycerol yeast extract agar as culture media. Seven bacteria: Escherichia coli, Bacillus spp, Pseudomonas spp, Azomonas spp, Gluconobacter spp, Micrococcus spp, and Staphylococcus aureus; five fungi: Rhizopus spp, Mucor spp, Rhodotorula app, Trichoderma spp, Aspergillus spp and one actinomycete: Actinomyces humiferus were isolated. These isolates were screened for their antimiocrobial potency against selected reference pathogenic organisms: Staphylococcus aureus, Pseudomonas aerugenosa, and Candida albicans. Bacillus spp isolated was found to inhibit Staphylococcus aureus and Pseudomonas aerugenosa, Actinomyces spp inhibited all the pathogens at different rate, fungal isolate, Rhizopus spp inhibited Staphylococcus aureus while the other fugal isolate did not inhibit any of the reference pathogens.

2015-10-01T00:00:00Z ABIODUN, OLUWASANMI EZEKIEL Gabriel-Ajobiewe, Ruth Adefolakemi O. http://repository.fuoye.edu.ng:80/handle/123456789/1205 2016-03-29T13:13:25Z 2015-10-01T00:00:00Z

Title: ISOLATION AND CHARACTERIZATION OF MICROORGANISMS ASSOCIATED WITH BIODEGRADATION OF THE AFRICAN WALNUT SHELLS USING CHICKEN DROPPINGS AS INNOCULUM Authors: ABIODUN, OLUWASANMI EZEKIEL; Gabriel-Ajobiewe, Ruth Adefolakemi O. Abstract: Microbial analyses were carried out on the shell of the edible nuts of African walnut (Tetracarpidium conophorum). This study was aimed at determining the microbial load of boiled and raw African walnut shell and chicken dropping which can be used as inoculums in biodegradation process in order to solve the problem of agro waste pollution in the environment. The nuts were sorted and washed with tap water to remove flesh residues and other contaminants and divided into two lots. The first lot was boiled for 1.5 h. The second lot was used raw; the raw nut and the boiled nut were then unshelled and the shells were dried at 60◦C for 5days in the oven. The dried shells were grind and analyzed. Bacterial and fungal evaluations of the shell from nut were done using the agar diffusion technique with serial dilutions of the grind shell and the same process for chicken droppings. Forty Grams (40g) of the grind walnut shells were weighed and put in a sterile cover bowl and 20ml of sterile distilled water was added to the samples under a sterile condition and was gently mixed with sterile spatula. The grind walnut shell and chicken dropping was done in Ratio 1:1 and 2:1. Microorganisms were isolated and identified. The microbial analysis revealed that the boiled shell accommodate a large number of microorganism compared to that of raw. The result show that the microorganisms present in the walnut shell were increasing as the day is increasing and latter begins to decrease.

2015-10-01T00:00:00Z AJAYI, FRANCISCA BOSEDE http://repository.fuoye.edu.ng:80/handle/123456789/1128 2016-04-04T13:04:34Z 2015-10-01T00:00:00Z

Title: COMPARATIVE EVALUATION OF THE MICROBIOLOGICAL QUALITY AND SENSORY PROPERTIES OF COFERMENTED MAIZE, CARROT, PIGEON PEA AND MILLET, SWEETPOTATO, PIGEON PEA. Authors: AJAYI, FRANCISCA BOSEDE Abstract: In Nigeria low-socio economic mothers use fermented cereals like maize (Zea mays) andMillet (Pennisetum americanum) as infants’ complementary food. Pigeon peas (Cajanus cajan L.) are underutilized legumes in Nigeria. This study co- fermented of maize, carrot/pigeon pea and millet, sweet potato/ pigeon pea were co-fermented in ratio 6:2:2 (w/w) and the fermented products were compared.Nutritional, viscosity and microbial status of co-fermented cereal,legumes, tubers and vegetable were studied.Products were analyzed for vitamins, reducing sugar, trypsin inhibitory activity, pH and Titratable acidity using standard methods. The predominant microorganisms isolated from both samples during fermentation period were Lactobacillus spp. Consistency properties were determined using Bostwick Consistometer. Vitamin B3 content was higher in the samples (p > 0.05) which is higher than recommended value. Vit B6 (Pyridoxine) and B1 (Thiamine) values were comparable torecommended values while some values were lower. In terms of organoleptic properties of the product co-fermented sample A ( maize, carrot/pigeon pea) was most preferred by the panelist with regards to color, taste, texture and aroma than sample that are not co-fermented. . Co-fermentation of maize, carrot/pigeon pea and millet, sweet potato/pigeon pea resulted in a product of improved nutritional quality than fermented maize.

2015-10-01T00:00:00Z